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PML And The JC Virus

December 8, 2012 by Sara

PMLTysabri is a dream come true for many individuals with Multiple Sclerosis. Personally, I have opted to take Gilenya (for now), but Tysabri was very tempting when I considered my options after it became apparent that Rebif would not work out for me any longer. However, along with Tysabri’s side effects comes one very sinister danger: PML. One patient on Gilenya has been diagnosed with PML, and it can happen to anyone whether or not they have MS. Knowing that medication (especially newer medications) may bring a risk of PML has frightened us all.

[Read more…] about PML And The JC Virus

Filed Under: diagnostic, doctor, lumbar puncture, mri, multiple sclerosis, neurologist, pml, tysabri Tagged With: disease, exacerbation, gilenya, infection, ms, ms attack, multiple sclerosis, neurological disorder, neurologist, pml, side effects, spinal tap, steroids, tysabri

Living With Multiple Sclerosis – Four Years

December 1, 2012 by Sara

Living With Multiple Sclerosis“They” say that you are considered newly diagnosed for the first 2 1/2 to 3 years after your Multiple Sclerosis diagnosis. It seems like only yesterday that I posted my “Year One” article. It seems like only yesterday that  I was diagnosed! Somehow, enough time has passed that I find myself at a point where I have been living with Multiple Sclerosis for four years.

[Read more…] about Living With Multiple Sclerosis – Four Years

Filed Under: bg-12, cannabis, ccsvi, cognitive dysfunction, depression, diet, doctor, exercise, fingolimod, gilenya, heat intolerance, insurance, lumbar puncture, mri, ms hug, multiple sclerosis, neurologist, rebif, research, stem cell therapy, symptoms, treatment Tagged With: disease, exacerbation, fingolimod, fty720, gilenya, ms, ms attack, ms hug, multiple sclerosis, muscle spasms, neurological disorder, neurologist, spasticity, vitamin d

Simplify Your Life – Part 1 – Finances

October 6, 2012 by Sara

simplify your lifeMultiple Sclerosis has certainly complicated my life in many ways. The varieties of stress that come along with modern life are compounded exponentially with this disease. I have new doctors now, excess weight, less energy, disability, handicap parking tags, canes, fans to cool me down, bottles upon bottles of medications, a CPAP machine, bills and statements from hospitals, and, last but not least, worries. A lot of worries. At times I have felt supremely overwhelmed with stuff, with concerns, with financial problems, with health problems, with responsibilities (dinner, dishes, laundry, shopping, cleaning, preparing for work). How do you simplify your life?

[Read more…] about Simplify Your Life – Part 1 – Finances

Filed Under: multiple sclerosis, stress management Tagged With: disease, ms, multiple sclerosis, neurological disorder, stress

One Big, Fat Topic: Multiple Sclerosis And Weight

September 29, 2012 by Sara

Multiple Sclerosis And WeightWhy is it unusual for us to talk about Multiple Sclerosis and weight? They both affect us so much and they do affect each other. But we often avoid acknowledging them together. Multiple Sclerosis itself isn’t the only part of having MS that affects our weight – all those drugs that we take for this that and the other play a large part in and of themselves. Between fast food, soda, genetically modified fruits and vegetables, and meat that has been filled with hormones and antibiotics, it’s a wonder we live long enough to even take the medications which alter our bodies on top of everything else. Not surprising that so many of us believe that diet and exercise play a large part in our disease course.

[Read more…] about One Big, Fat Topic: Multiple Sclerosis And Weight

Filed Under: diet, exercise, multiple sclerosis, treatment Tagged With: disease, mobility, ms, multiple sclerosis, neurological disorder

Introducing Aubagio

September 16, 2012 by Sara

AubagioLast week Sanofi SA’s oral drug for Multiple Sclerosis, Aubagio (also known as Teriflunomide and A77 1726), was approved by the FDA. Somehow this one snuck under my radar and here we are with it scheduled to be prescribed by October 1st!

First, the bad news: studies show that it’s no more effective than Rebif (and maybe less effective). With Gilenya already on the market and BG-12 looming, I doubt that this drug will make a huge impact. It is related to an existing arthritis drug, leflunomide.

The good news is that it does work compared with placebo and is generally safe and well-tolerated. Because it acts differently than interferons, it may also make patients less susceptible to infections. The more choices we have for treatment, the better.

[Read more…] about Introducing Aubagio

Filed Under: aubagio, multiple sclerosis, treatment Tagged With: aubagio, disease, ms, ms attack, multiple sclerosis, neurological disorder, pill

Agenda Acthar

September 8, 2012 by Sara

ActharHave you heard of Acthar Gel, a new treatment for Multiple Sclerosis relapses? Surprise – this drug has been around for decades, originally approved in 1952. Acthar was essentially abandoned in the 1980’s when bested by methylprednisolone.

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Filed Under: multiple sclerosis, neurologist, treatment

Linking Depression And Multiple Sclerosis

September 1, 2012 by Sara

Depression And Multiple SclerosisDepression and Multiple Sclerosis are inherently linked. Depression is not something that solely affects those of us with MS, and it is often underreported or undiagnosed.

While many individuals without MS experience depression and many individuals with MS may never experience it, more than 50% of individuals with MS will experience some form of depression during their lives. At any given time at least 17% of us will be depressed in one way or another. But there is hope, there is treatment, and there is possible prevention.

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Filed Under: depression, multiple sclerosis, ssri, symptoms, treatment Tagged With: depression, disease, interferon, ms, multiple sclerosis, neurological disorder

BG-12: The New Normal For MS Treatment?

August 25, 2012 by Sara

BG-12BG-12 (Dimethyl Fumarate) has not yet been approved for use, but trials have been overwhelmingly positive for this low-risk oral drug. Approved for Fast Track (10 months of review) by the FDA on February 28 2012, BG-12 should be available to Relapsing-Remitting MS patients and possibly for individuals with rheumatoid arthritis as a pill taken 2 or 3 times daily before 2013. The European Union, Canada and Switzerland are also currently reviewing this drug.

In addition to rheumatoid arthritis, Dimethyl Fumarate (DMF) is also being studied for its effects on lupus and cancer. DMF is a Fumaric Acid Ester which has been used to treat psoriasis since 1959.

Neurologists around the world are already planning to make this their go-to first line treatment for patients with Multiple Sclerosis even though Biogen Idec (the company behind Avonex and Tysabri) has not yet released a price profile of the drug. Why is BG-12 expected to quickly become the world’s leading MS treatment?

[Read more…] about BG-12: The New Normal For MS Treatment?

Filed Under: bg-12, multiple sclerosis, neurologist, treatment Tagged With: bg-12, disease, ms, ms attack, multiple sclerosis, neurological disorder, neurologist, pill

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